Phytochemistry 2002-12-01

Meroterpenes from Penicillium sp found in association with Melia azedarach.

Regina M Geris dos Santos, Edson Rodrigues-Fo

Index: Phytochemistry 61(8) , 907-12, (2002)

Full Text: HTML

Abstract

A Penicillium sp was isolated from the root bark of Melia azedarach and cultivated over sterilized rice. After chromatographic procedures, two meroterpenes, named preaustinoid A and B, were obtained in addition to the known alkaloid verruculogen. Their structures were identified by extensive spectroscopic studies, and they exhibited moderate bacteriostatic effects on Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus sp.