e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron
Chemistry of dinitroacetonitrile—II: Derivatives of dinitroacetonitrile from Michael, Mannich and alkylation reactions, 2, 2-dinitro-2-cyanoethanol and its derivatives
CO Parker, WD Emmons, AS Pagano, HA Rolewicz…
Index: Parker,C.O. et al. Tetrahedron, 1962 , vol. 17, p. 89 - 104
Addition of dinitroacetonitrile to carbonyl conjugated unsaturated systems was a generally successful reaction for the preparation of Michael adducts. The expected products were obtained with methyl acrylate, acrylamide, acrolein, butenone, methylene-bis-acrylamide, and N, N′, N ″-triacrylylper-hydro-s-triazine. Acrylic acid gave three products: the normal adduct, the corresponding carbamyl derivative and its cyclic imide. Dinitrocyanoethanol ...
