Journal of the American Chemical Society 2010-11-24

Palladium-catalyzed aminosulfonylation of aryl halides.

Bao Nguyen, Edward J Emmett, Michael C Willis

Index: J. Am. Chem. Soc. 132 , 16372-16373, (2010)

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Abstract

The palladium-catalyzed three-component coupling of aryl iodides, sulfur dioxide, and hydrazines to deliver aryl N-aminosulfonamides is described. The colorless crystalline solid DABCO·(SO(2))(2) was used as a convenient source of sulfur dioxide. The reaction tolerates significant variation of both the aryl iodide and hydrazine coupling partners.