Angewandte Chemie. International edition in English 2009-01-01

Polypyrrole nanotubes conjugated with human olfactory receptors: high-performance transducers for FET-type bioelectronic noses.

Hyeonseok Yoon, Sang Hun Lee, Oh Seok Kwon, Hyun Seok Song, Eun Hae Oh, Tai Hyun Park, Jyongsik Jang

Index: Angew. Chem. Int. Ed. Engl. 48(15) , 2755-8, (2009)

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Abstract

Get a whiff of this: Human olfactory receptor (hOR)-conjugated polypyrrole (PPy) nanotubes were integrated into the field-effect transistor (FET) sensor platform for the fabrication of high-performance bioelectronic noses (see picture, S = source, D = drain). The device can translate and amplify hOR-odorant interaction into a detectable signal, and it showed highly sensitive and specific responses toward a target odorant.