Journal of Organic Chemistry 2009-03-20

Stereoselective one-pot, three-component synthesis of 4-aryltetrahydropyran via Prins-Friedel-Crafts reaction.

U C Reddy, S Bondalapati, Anil K Saikia

Index: J. Org. Chem. 74(6) , 2605-8, (2009)

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Abstract

A diastereoselective one-pot, three-component Prins-Friedel-Crafts reaction was developed for the synthesis of 4-aryltetrahydropyran derivatives from the reaction of carbonyl compounds with homoallylic alcohol in the presence of arene promoted by boron trifluoride etherate.