A series of pseudopeptide analogues of the C-terminal heptapeptide of cholecystokinin in which each peptide bond, one at a time, has been replaced by a CH2NH bond were synthesized: Z-Tyr (S03-)-Nle-Gly-Trp-Nle-Asp $-(CHzNH) P he-NH2 (1 1, Z-Tyr (SO,-)-Nle- Gly-Trp-Nle $(CH2NH) Asp-Phe-NH2 (2), Z-Tyr (SO,-)-Nle-Gly-Trp $-
[Griffin, Martin; Mongeot, Alexandre; Collighan, Russell; Saint, Robert E.; Jones, Richard A.; Coutts, Ian G.C.; Rathbone, Daniel L. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 20 p. 5559 - 5562]