Journal of Bacteriology 2011-09-01

Genome sequence of the thermophilic strain Bacillus coagulans 2-6, an efficient producer of high-optical-purity L-lactic acid.

Fei Su, Bo Yu, Jibin Sun, Hong-Yu Ou, Bo Zhao, Limin Wang, Jiayang Qin, Hongzhi Tang, Fei Tao, Michael Jarek, Maren Scharfe, Cuiqing Ma, Yanhe Ma, Ping Xu

Index: J. Bacteriol. 193(17) , 4563-4, (2011)

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Abstract

Bacillus coagulans 2-6 is an efficient producer of lactic acid. The genome of B. coagulans 2-6 has the smallest genome among the members of the genus Bacillus known to date. The frameshift mutation at the start of the d-lactate dehydrogenase sequence might be responsible for the production of high-optical-purity l-lactic acid.