Indian Journal of Biochemistry and Biophysics 1998-10-01

Comparison of the antioxidant action of the alcoholic extract of Rubia cordifolia with rubiadin.

Y B Tripathi, M Sharma

Index: Indian J. Biochem. Biophys. 35(5) , 313-6, (1998)

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Abstract

The inhibition of FeSO4 induced lipid peroxidation in rat liver by alcoholic extract of Rubia cordifolia and by one of its constituent rubiadin (1, 3-dihydroxy-2-methyl anthraquinone) (pure form) has been compared. Both have been found to inhibit lipid peroxidation in a dose dependent manner. Whereas the former shows both oxidising and reducing properties with Fe2+ and Fe3+, the latter shows oxidising property only by converting Fe2+ to Fe3+. The former inhibits the oxidation of reduced glutathione while the latter does not.