Potential antitumor agents. Some 1, 6-disubstituted galactitol and mannitol derivatives

EM Acton, M Keyanpour-Rad, JE Christensen…

Index: Acton,E.M. et al. Carbohydrate Research, 1972 , vol. 22, p. 477 - 486

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Citation Number: 11

Abstract

28 29 to water-soluble products. This indicated a degree of strain in the dioxolane rings of 29 that was unexpected, even though it was recognized that two unfavored EC-rings 7, 16V17 (namely, having the adjacent ring-substituents cis) are joined in this molecule. In contrast, the 2, 4: 3, 5 isomer (14) was perfectly stable and could be converted into a crystalline bis (p-toluenesulfonate) or bis (methanesulfonate)(15). Any tendency toward ...