Bulletin of Experimental Biology and Medicine 2011-01-01

Role of the brain dopaminergic and opioid system in the regulation of "child's" (maternal bonding) behavior of newborn albino rats.

I S Stovolosov, V A Dubynin, A A Kamensky

Index: Bull. Exp. Biol. Med. 150(3) , 281-5, (2011)

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Abstract

Administration of D(2) receptor antagonist clebopride in a dose not affecting locomotor activity was followed by a decrease in maternal bonding behavior of 10-day-old and 15-day-old albino rat pups. D(1) receptor antagonist SCH23390 had a stimulatory effect only on the behavior of 10-day-old newborns. Opioid peptide β-casomorphin-7 abolished the effect of clebopride in rat pups of the older age group.