Journal of Chromatography B 2006-07-11

LC-ESI-MS/MS determination of phenylurea and triazine herbicides and their dealkylated degradation products in oysters.

E Bichon, M Dupuis, B Le Bizec, F André

Index: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 838(2) , 96-106, (2006)

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Abstract

A method was developed for the determination of several phenylurea and triazine herbicides and their transformation products in oysters at the low microg/kg level. Pressurised liquid extraction (PLE) of lyophilisated samples had required successive SPE combined with a liquid/liquid extraction to provide relatively clean extracts for the determination in LC-MS/MS. This procedure was validated according to the 2002/657/EC analytical decision. Efficiency of the analytical method led to confirmatory CCalpha values ranging from 0.1 to 14 microg/kg with an R.S.D. value ranging from 14% to 66% and a recovery yield ranging from 32% to 46% for phenylureas and from 29% to 75% for triazines.