Tetrahedron Letters

NbCl 5 mediated deprotection of methoxy methyl ether

JS Yadav, B Ganganna, DC Bhunia, P Srihari

Index: Yadav; Ganganna; Bhunia, Dinesh C.; Srihari Tetrahedron Letters, 2009 , vol. 50, # 30 p. 4318 - 4320

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Citation Number: 22

Abstract

The selective introduction and removal of protective groups is an important tool which plays a significant role in the area of total synthesis of complex, biologically potent molecules. 1 Hydroxyl groups are the major functionalities found in large no. of intermediate compounds utilized in multi step synthesis. Of the several protective groups developed so far to proceed ahead in the target synthesis, methoxymethyl chloride can be considered as one of the most commonly ...