Tetrahedron Letters

Amidation through carbamates

A Latorre, S Rodríguez, J Izquierdo, FV González

Index: Latorre, Antonio; Rodriguez, Santiago; Izquierdo, Javier; Gonzalez, Florenci V. Tetrahedron Letters, 2009 , vol. 50, # 22 p. 2653 - 2655

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Citation Number: 3

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... N-Alkyl carbamates of primary amines are easily converted into amides under treatment with Grignard reagents. Consequently, primary amines can be converted into amides in a one-pot reaction through carbamate protection and Grignard addition. ... Carbamates and amides are ...

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