Cu (OTf) 2-mediated fluorination of aryltrifluoroborates with potassium fluoride

…, SD Schimler, PS Hanley, MS Sanford

Index: Ye, Yingda; Sanford, Melanie S. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4648 - 4651

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Citation Number: 68

Abstract

This Communication describes the Cu (OTf) 2-mediated fluorination of aryltrifluoroborates with KF. The reaction proceeds under mild conditions (at 60° C over 20 h) and shows a broad substrate scope and functional group tolerance. The Cu is proposed to play two separate roles in this transformation:(1) as a mediator for the aryl–F coupling and (2) as an oxidant for accessing a proposed CuIII (aryl)(F) intermediate.