Sexually Transmitted Diseases 2011-03-01

The usefulness of toluidine red unheated serum test in the diagnosis of HIV-negative neurosyphilis.

Ying Jiang, Xiaohong Chen, Xiaomeng Ma, Yu Yang, Fuhua Peng, Xueqiang Hu

Index: Sex. Transm. Dis. 38(3) , 244-5, (2011)

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Abstract

We retrospectively analyzed the Venereal Disease Research Laboratory test, Treponema pallidum particle agglutination test, and toluidine red unheated serum test (TRUST) in 41 cases of HIV-negative neurosyphilis and 34 non-neurologic syphilitic patient and found that serum-TRUST titers could be the indication of lumbar puncture in syphilitic patients and a reactive cerebrospinal fluid-TRUST is considered diagnostic to neurosyphilis.