Antimicrobial Agents and Chemotherapy 1977-03-01

Antibiotic metabolites from a marine pseudomonad.

S J Wratten, M S Wolfe, R J Andersen, D J Faulkner

Index: Antimicrob. Agents Chemother. 11(3) , 411-4, (1977)

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Abstract

An antibiotic-producing pseudomonad was isolated from a seawater sample from a La Jolla, Calif., tidepool. The pseudomonad produces two novel antibacterial compounds, 2-n-pentyl-4-quinolinol and 2-n-heptyl-4-quinolinol. It also synthesizes indole-3-carboxaldehyde, 6-bromoindole-3-carboxaldehyde, and the known antibiotic p-hydroxybenzaldehyde. Each of these compounds was identified by analysis of spectral data, and the structures were confirmed by synthesis or comparison with authentic samples.