Formation of aromatic amidoximes with hydroxylamine using microreactor technology

…, Z Baán, P Mizsey, Z Finta

Index: Voeroes, Attila; Baan, Zoltan; Mizsey, Peter; Finta, Zoltan Organic Process Research and Development, 2012 , vol. 16, # 11 p. 1717 - 1726

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Citation Number: 7

Abstract

In this contribution, the application of microreactor technology for amidoxime formation is demonstrated, with different aromatic nitriles reacted with a 50% solution of hydroxylamine (HA) under homogeneous conditions to reach full conversion. All reactions were executed in the presence of an excess of HA at an elevated temperature near to T onset of HA, but in safe mode. Upscaling was performed with success by the adaptation of an increased ...