Journal of Antibiotics 1997-06-01

Dihydrophencomycin methyl ester, a new phenazine derivative from a marine Streptomycete.

K Pusecker, H Laatsch, E Helmke, H Weyland

Index: J. Antibiot. 50(6) , 479-83, (1997)

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Abstract

The novel 5,10-dihydrophencomycin methyl ester (4) and the known microbial metabolites (2-hydroxyphenyl)-acetamide (1), menaquinone MK9 (II, III, VIII, IX-H8) (2), and phencomycin (3a) were isolated from an unidentified marine Streptomyces sp. and the structures were elucidated by NMR methods. Compound 4 shows weak antibiotic activity against Escherichia coli and Bacillus subtilis.