Organic & Biomolecular Chemistry 2003-04-07

Dendritic metalloporphyrins with a distal H-bond donor as mimics of haemoglobin.

Beatrice Felber, Carlos Calle, Paul Seiler, Arthur Schweiger, François Diederich

Index: Org. Biomol. Chem. 1(7) , 1090-93, (2003)

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Abstract

We report the synthesis of iron(II) porphyrins functionalised with first- and second-generation dendrons as mimics of haemoglobin. The porphyrin core bears an ethynyl linker pointing towards the centre of the molecule, in an ideal position for the introduction of a series of distal ligands as potential H-bond donors by Pd0-catalysed Sonogashira cross-coupling.