Tetrahedron letters

Iodine catalyzed conjugate addition of mercaptans to α, β-unsaturated carboxylic acids under solvent-free condition

S Gao, T Tzeng, MNV Sastry, CM Chu, JT Liu, C Lin…

Index: Gao, Shijay; Tzeng, Tingkai; Sastry; Chu, Cheng-Ming; Liu, Ju-Tsung; Lin, Chunchi; Yao, Ching-Fa Tetrahedron Letters, 2006 , vol. 47, # 12 p. 1889 - 1893

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Citation Number: 54

Abstract

We have described herein molecular iodine catalyzed Michael addition of thiol to α, β- unsaturated carboxylic acids. This environmentally benign catalytic system (iodine) used under mild and solvent-free conditions to achieve the corresponding adducts in excellent yield.