Bioorganic & Medicinal Chemistry 2013-12-01

Trisubstituted and tetrasubstituted pyrazolines as a novel class of cell-growth inhibitors in tumor cells with wild type p53

Mohammad Abdel-Halim, Adam B. Keeton, Evrim Gurpinar, Bernard D. Gary, Simon M. Vogel, Matthias Engel, Gary A. Piazza, Frank M. Boeckler, Rolf W. Hartmann, Ashraf H. Abadi

Index: Bioorg. Med. Chem. 21(23) , 7343-56, (2013)

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Abstract

Designing the new pyrazoline derivatives based on the structure of the reference compounds I–V.