Organic Letters 2012-04-20

Efficient construction of fused indolines with a 2-quaternary center via an intramolecular Heck reaction with a low catalyst loading.

Lei Zhao, Ziyuan Li, Lin Chang, Jinyi Xu, Hequan Yao, Xiaoming Wu

Index: Org. Lett. 14(8) , 2066-9, (2012)

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Abstract

An efficient construction of fused indolines with a 2-quaternary center through a palladium-catalyzed intramolecular Heck reaction of N-(2(2-halobenzoxyl)-2,3-disubstituted indoles is disclosed. This protocol provided a straightforward access to diverse fused indolines with good functional group tolerance.© 2012 American Chemical Society