Synthesis and antifungal activity against strains of candida albicans of 6??fluoro??4 (5 or 7)??chloro??2??(difluorobenzoyl) aminobenzothiazoles

D Armenise, N De Laurentis, A Reho…

Index: Armenise, Domenico; De Laurentis, Nicolino; Reho, Antonia; Rosato, Antonio; Morlacchi, Flaviano Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 5 p. 771 - 775

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Citation Number: 10

Abstract

Abstract A series of 6-fluoro-4-(5 or 7)-chloro-2-(difluorobenzoyl) aminobenzothiazoles 3a-r were prepared to investigate their potential biological activity. In this work, the results of their in vitro antifungal activity against some strains of Candida albicans are reported. It was found that some derivatives displayed antifungal activity higher than that for 3k [1a] compound already described in literature.