Syntheses of aryl glyoxylate. I. The reaction of alkyl dichloro (alkoxy) acetates with aromatics in the presence of Lewis acid.

…, I Nomura, T Takanaga, T Sugita, K Ichikawa

Index: Itoh, Osamu; Nagata, Takayoshi; Nomura, Isamu; Takanaga, Tetsuya; Sugita, Toshio; Ichikawa, Katsuhiko Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 3 p. 810 - 814

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Citation Number: 14

Abstract

Ethyl dichloro (ethoxy) acetate (1) and methyl dichloro (methoxy) acetate (2) were characterized. The reaction of 1 and 2 with aromatics in the presence of AlCl 3 gave a considerable yield of aromatic α-keto ester. The aromatics included mono-and polymethylbenzene and anisol. The reaction was studied under various conditions and the results were compared with the acylation by ethoxalyl or methoxalyl chloride. The reaction ...