Bioorganic & Medicinal Chemistry 2005-06-01

Synthesis, characterisation and cytotoxicity of chloro derivatives of prenylnaphthohydroquinone.

Aurora Molinari, Alfonso Oliva, Claudia Ojeda, Jorge Escobar, Carolina Gallardo, José Ma Miguel del Corral, Ma Angeles Castro, Carmen Cuevas, Arturo San Feliciano

Index: Bioorg. Med. Chem. 13(11) , 3841-6, (2005)

Full Text: HTML

Abstract

From the Diels-Alder adduct between alpha-myrcene and 2-chloro-1,4-benzoquinone, a family of chloro derivatives of prenylnaphthohydroquinone have been synthesised and evaluated for their cytotoxicity against 14 neoplastic cell lines.