Solvent Effects on the Structure-Property Relationship of Some Potentially Pharmacologically Active 3-(4-Substituted Benzyl)-5-Ethyl-5-Phenyl-and 3-(4-Substituted …

…, NP Trišović, NV Valentić, GS Ušćumlić

Index: Hmuda, Sleem F.; Trisovic, Nemanja P.; Valentic, Natasa V.; Uscumlic, Gordana S. Journal of Solution Chemistry, 2011 , vol. 40, # 2 p. 307 - 319

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Citation Number: 10

Abstract

Abstract Two series of 3-(4-substituted benzyl)-5-ethyl-5-phenyl-and 3-(4-substituted benzyl)- 5, 5-diphenylhydantoins were synthesized and their UV absorption spectra were recorded in the region 200–400 nm in selected solvents of different polarity. The effects of solvent dipolarity/polarizability and solvent/solute hydrogen bonding interactions on the spectral shifts were analyzed by means of the linear solvation energy relationship (LSER) ...