e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Removal of fluorine from and introduction of fluorine into polyhalopyridines: an exercise in nucleophilic hetarenic substitution

C Bobbio, T Rausis, M Schlosser

Index: Chemistry - A European Journal, , vol. 11, # 6 p. 1903 - 1910

Full Text: HTML

Citation Number: 29

Abstract

... Chemistry – A European Journal: Previous article in issue: Zirconocene-Mediated ... Manfred Schlosser Prof. E-mail address: manfred.schlosser@epfl.ch. Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale, BCh, 1015 Lausanne, Switzerland. ...

3,5-Difluoro-2-hydrazinopyridine Structure

3,5-Difluoro-2-...

~%

4-Chloro-3,5-difluoropyridine Structure

4-Chloro-3,5-di...

2,3,5,6-Tetrafluoropyridine Structure

2,3,5,6-Tetrafl...

~%

4-Chloro-3,5-difluoropyridine Structure

4-Chloro-3,5-di...

3-chloro-2,5,6-trifluoropyridine Structure

3-chloro-2,5,6-...

~%

2,5-Difluoropyridine Structure

2,5-Difluoropyridine

3-Chlorotetrafluoropyridine Structure

3-Chlorotetrafl...

~%

2,5-Difluoropyridine Structure

2,5-Difluoropyridine

(3,5,6-trifluoropyridin-2-yl)hydrazine Structure

(3,5,6-trifluor...

~%

4-Chloro-3,5-difluoropyridine Structure

4-Chloro-3,5-di...

Pentafluoropyridine Structure

Pentafluoropyridine

~%

4-Chloro-3,5-difluoropyridine Structure

4-Chloro-3,5-di...

2,3,5-Trifluoropyridine Structure

2,3,5-Trifluoro...

~%

4-Chloro-3,5-difluoropyridine Structure

4-Chloro-3,5-di...

5-Chloro-2,3-difluoropyridine Structure

5-Chloro-2,3-di...

~%

4-Chloro-2,3-difluoropyridine Structure

4-Chloro-2,3-di...

5-Chloro-2,3-difluoropyridine Structure

5-Chloro-2,3-di...

~%

trifluoroperazine Structure

trifluoroperazine

2,3-Difluoropyridine Structure

2,3-Difluoropyridine

~%

trifluoroperazine Structure

trifluoroperazine

3-Chloro-4,5-difluoropyridine Structure

3-Chloro-4,5-di...

~%

4-Chloro-3-fluoropyridine Structure

4-Chloro-3-fluo...

3,4-Dichloro-5-fluoropyridine Structure

3,4-Dichloro-5-...

~%

4-Chloro-3-fluoropyridine Structure

4-Chloro-3-fluo...

5-CHLORO-3-FLUORO-2-HYDRAZINYLPYRIDINE Structure

5-CHLORO-3-FLUO...

~%

4-Chloro-3-fluoropyridine Structure

4-Chloro-3-fluo...

5-Chloro-2,3-difluoropyridine Structure

5-Chloro-2,3-di...

~%

4-Chloro-3-fluoropyridine Structure

4-Chloro-3-fluo...

3-Chloro-5-fluoropyridine Structure

3-Chloro-5-fluo...

~%

4-Chloro-3-fluoropyridine Structure

4-Chloro-3-fluo...

3-chloro-2,5,6-trifluoropyridine Structure

3-chloro-2,5,6-...

~%

3-Chloro-2,5-difluoropyridine Structure

3-Chloro-2,5-di...

3-Chlorotetrafluoropyridine Structure

3-Chlorotetrafl...

~%

3-Chloro-2,5-difluoropyridine Structure

3-Chloro-2,5-di...

3-chloro-2,5,6-trifluoropyridine Structure

3-chloro-2,5,6-...

~72%

2,3,6-TRIFLUOROPYRIDINE Structure

2,3,6-TRIFLUORO...

3-Chlorotetrafluoropyridine Structure

3-Chlorotetrafl...

~%

2,3,6-TRIFLUOROPYRIDINE Structure

2,3,6-TRIFLUORO...

2,3,4,6-tetrafluoropyridine Structure

2,3,4,6-tetrafl...

~%

2,3,6-TRIFLUOROPYRIDINE Structure

2,3,6-TRIFLUORO...

Pentafluoropyridine Structure

Pentafluoropyridine

~%

3,5-Difluoropyridine Structure

3,5-Difluoropyridine

(3,5,6-trifluoropyridin-2-yl)hydrazine Structure

(3,5,6-trifluor...

~%

3,5-Difluoropyridine Structure

3,5-Difluoropyridine

2,3,5,6-Tetrafluoropyridine Structure

2,3,5,6-Tetrafl...

~%

3,5-Difluoropyridine Structure

3,5-Difluoropyridine

2,3,5-Trifluoropyridine Structure

2,3,5-Trifluoro...

~%

3,5-Difluoropyridine Structure

3,5-Difluoropyridine

2,4,6-trifluoro-3-(triethylsilyl)pyridine Structure

2,4,6-trifluoro...

~%

2,4-Difluoropyridine Structure

2,4-Difluoropyridine

2,4-difluoro-6-hydrazino-3-(triethylsilyl)pyridine Structure

2,4-difluoro-6-...

~%

2,4-Difluoropyridine Structure

2,4-Difluoropyridine

3,4-Dichloro-2-fluoropyridine Structure

3,4-Dichloro-2-...

~%

2,4-Difluoropyridine Structure

2,4-Difluoropyridine

2,4,6-Trifluoropyridine Structure

2,4,6-Trifluoro...

~%

2,4-Difluoropyridine Structure

2,4-Difluoropyridine

3-Chloro-2-fluoropyridine Structure

3-Chloro-2-fluo...

~%

2,4-Difluoropyridine Structure

2,4-Difluoropyridine

2-Fluoropyridine Structure

2-Fluoropyridine

~%

2,4-Difluoropyridine Structure

2,4-Difluoropyridine

3,5-Dichloro-2,4,6-trifluoropyridine Structure

3,5-Dichloro-2,...

~%

2,4-Difluoropyridine Structure

2,4-Difluoropyridine

3-Chloro-2-fluoropyridine Structure

3-Chloro-2-fluo...

~%

3-Chloro-2,4-difluoropyridine Structure

3-Chloro-2,4-di...

2-Fluoropyridine Structure

2-Fluoropyridine

~%

3-Chloro-2,4-difluoropyridine Structure

3-Chloro-2,4-di...

2,3,5,6-Tetrafluoropyridine Structure

2,3,5,6-Tetrafl...

~%

2,3,5-Trifluoropyridine Structure

2,3,5-Trifluoro...

Pentafluoropyridine Structure

Pentafluoropyridine

~%

2,3,5-Trifluoropyridine Structure

2,3,5-Trifluoro...

3,5-Difluoro-2-hydrazinopyridine Structure

3,5-Difluoro-2-...

~%

3,4,5-Trifluoropyridine Structure

3,4,5-Trifluoro...

(3,5,6-trifluoropyridin-2-yl)hydrazine Structure

(3,5,6-trifluor...

~%

3,4,5-Trifluoropyridine Structure

3,4,5-Trifluoro...

2,3,5,6-Tetrafluoropyridine Structure

2,3,5,6-Tetrafl...

~%

3,4,5-Trifluoropyridine Structure

3,4,5-Trifluoro...

Pentafluoropyridine Structure

Pentafluoropyridine

~%

3,4,5-Trifluoropyridine Structure

3,4,5-Trifluoro...

2,3,5-Trifluoropyridine Structure

2,3,5-Trifluoro...

~%

3,4,5-Trifluoropyridine Structure

3,4,5-Trifluoro...

3,5-Difluoropyridine Structure

3,5-Difluoropyridine

~%

3,4,5-Trifluoropyridine Structure

3,4,5-Trifluoro...

Removal of fluorine from and introduction of fluorine into p...

[Bobbio, Carla; Rausis, Thierry; Schlosser, Manfred Chemistry - A European Journal, 2005 , vol. 11, # 6 p. 1903 - 1910]