Bioscience, Biotechnology, and Biochemistry 2010-01-01

Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava.

Samah Shabana, Azusa Kawai, Kenji Kai, Kohki Akiyama, Hideo Hayashi

Index: Biosci. Biotechnol. Biochem. 74 , 878-880, (2010)

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Abstract

Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4'-O-beta-D-glucopyranoside was isolated from Allium cepa as a urease inhibitor with an IC(50) value of 190 microM-. Quercetin and two quercetin glycosides, avicularin and guaijaverin, were isolated from Psidium guajava as urease inhibitors with respective IC(50) values of 80 microM-, 140 microM-, and 120 microM-.