Pyridazines with heteroatom substituents in position 3 and 5, part 1: 5-Hydroxy-3 (2H)-pyridazinone and its derivatives

UG Wagner, C Kratky, T Kappe

Index: Wagner, Ulrike Gabriella; Kratky, Christoph; Kappe, Thomas Monatshefte fuer Chemie, 1989 , vol. 120, p. 329 - 342

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Citation Number: 8

Abstract

Summary. The synthesis of the title compound 7 was achieved starting with mucochloric acid via the pyridazinones 1, 2 and 6. The electrolytic ionisation constants for 7 were found to be 4.81 (_+ 0.03) and - 0.3 (_+ 0.3). Crystal structure analyses were performed for 7 and its "fixed" derivatives 6 and 9. ... Keywords. Synthesis of 5-methoxy- and 5-hydroxy-3(2H)-pyridazinones; pK, Values of 5-hydroxy- 3(2H)-pyridazinone; Crystal structure of 3(2//)-pyridazinones.