Roumanian archives of microbiology and immunology 1998-01-01

Synthesis and molecular mechanical studies of antiviral copper(II) complexes with morpholinebiguanide drug.

G Patrinoiu, L Patron, J Weinberg, S Nita, A Meghea

Index: Roum. Arch. Microbiol. Immunol. 57(3-4) , 279-93, (1998)

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Abstract

The synthesis and characterization of new Cu(II) complexes with morpholinebiguanide drug are described. The complexes formed have been characterized by elemental analysis, IR, UV-VIS, conductance measurements, EPR spectra and magnetic susceptibility measurements. Their biological activity is supported by the experimental data and enhanced by the theoretical ones. The morpholinebiguanide ligand and their copper(II)-complexes were studied by molecular mechanics program.