Journal of Pharmacy and Pharmacology 1983-07-01

The deamination of n-pentylamine by monoamine oxidase and a semicarbazide-sensitive amine oxidase of rat heart.

C Guffroy, C J Fowler, M Strolin Benedetti

Index: J. Pharm. Pharmacol. 35(7) , 416-20, (1983)

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Abstract

n-Pentylamine is deaminated by homogenates of rat heart. Clorgyline inhibition curves at 10 and 100 microM n-pentylamine indicated that this substrate was deaminated by MAO-A, -B and a clorgyline-resistant amine oxidase sensitive to inhibition by semicarbazide. These results have been compared with two other commonly used monoamine substrates, beta-phenethylamine and benzylamine.