e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Highly diastereoselective additions to polyhydroxylated pyrrolidine cyclic imines: ready elaboration of aza??sugar scaffolds to create diverse carbohydrate??processing …
TM Chapman, S Courtney, P Hay…
Index: Chapman, Timothy M.; Courtney, Steve; Hay, Phil; Davis, Benjamin G. Chemistry - A European Journal, 2003 , vol. 9, # 14 p. 3397 - 3414
Abstract Representative diastereomeric, erythritol and threitol polyhydroxylated pyrrolidine imine scaffolds have been rapidly elaborated to diversely functionalized aza-sugars through highly diastereoselective organometallic (RM) additions (R= Me, Et, allyl, hexenyl, Ph, Bn, pMeO-Bn). The yields for these additions have all been substantially enhanced from previously optimised levels (< 58%) for normal additions using a reverse addition ...