Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2011-01-01

Genotoxicity assessment of ethylenediamine dinitrate (EDDN) and diethylenetriamine trinitrate (DETN)

Gunda Reddy, Jian Song, Paul Kirby, Mark S. Johnson, Gunda Reddy, Jian Song, Paul Kirby, Mark S. Johnson

Index: Mutat. Res. 726(2) , 169-74, (2011)

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Abstract

Highlights ► Ethylenediamine dinitrate and diethylenetriamine trinitrate are explosive compounds. ► A standard genetic toxicity battery was used to evaluate genotoxicity potentials. ► Ethylenediamine dinitrate was mutagenic only in strain TA 100. ► Diethylenetriamine trinitrate was negative in all genetic toxicity tests. ► These results show the in vivo and in vitro genotoxicity potentials.