Analyst (Cambridge UK) 2014-04-07

Novel reversible and selective nerve agent simulant detection in conjunction with superoxide "turn-on" probing.

Yoon Jeong Jang, Dhiraj P Murale, David G Churchill

Index: Analyst 139(7) , 1614-7, (2014)

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Abstract

Herein, we present fluorescein as a reversible fluorescent sensor for nerve agent simulants diethylchlorophosphate (DCP), diethyl methylphosphonate (DEMP), and diethyl cyanophosphonate (DECP). The superoxide allows for an "off-on" mechanism to regenerate fluorescein. The order of decrease in fluorescence intensity for nerve agent simulants is DCP > DEMP ≫ DECP.