2??Metylthiazolium salts as 1, 4??dinucleophiles. Thiazolo [3, 2??a] pyridinium salts from westphal condensation

…, JL Navio, J Alvarez??Builla

Index: Galera, C.; Vaquero, J. J.; Navio, Garcia J. L.; Alvarez-Builla, J. Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 1889 - 1892

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Citation Number: 9

Abstract

Westphal condensation [1,2] (Scheme 1) allows the syn- thesis of quinolizinium derivatives from N-substituted 2-methylpyridinium salts with 1,2-diketones. After addi- tions from several authors [3-91 the method seems to be simple and extremely versatile. Extension of the general process is being studied by our group as the method could provide a way to straightforward preparation of quater- nary nitrogen bridgehead heterocycles of great chemical and biological ...