Metallomics 2011-01-01

Synthesis, structure and biological evaluation of bis salicylaldehyde-4(N)-ethylthiosemicarbazone ruthenium(iii) triphenylphosphine.

R Prabhakaran, P Kalaivani, R Jayakumar, M Zeller, A D Hunter, S V Renukadevi, E Ramachandran, K Natarajan

Index: Metallomics 3(1) , 42-8, (2011)

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Abstract

Bis salicylaldehyde-4(N)-ethylthiosemicarbazone ruthenium(iii) triphenylphosphine [Ru(Sal-etsc)(H-Sal-etsc)(PPh(3))] was synthesized and structurally characterized by spectral and X-ray crystallographic studies and it showed 100% inhibition on the DPPH radical. It also exhibited a significant lymphocyte activity and inhibitory effect on the lung carcinoma A549 cell.