Facile eco-friendly synthesis of novel chromeno [4, 3-b] pyridine-2, 5-diones and evaluation of their antimicrobial and antioxidant properties

…, SK Gangisetty, MR Ganesh, G Gaddamanugu

Index: Jaggavarapu, Satyanarayana Reddy; Kamalakaran, Anand Solomon; Jalli, Ventkata Prasad; Gangisetty, Sravan Kumar; Ganesh, Munusswamy Ramanujam; Gaddamanugu, Gopikrishna Journal of Chemical Sciences, 2014 , vol. 126, # 1 p. 187 - 195

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Citation Number: 4

Abstract

Abstract Rapid and facile access to novel chromeno [4, 3-b] pyridine-2, 5-dione derivatives was achieved by a mild base catalysed reaction of 4-chloro-3-formylcoumarin and acetoacetamides in PEG-300 as recyclable solvent. The compounds were evaluated for their antimicrobial activities against 3 Gram-positive and 3 Gram-negative bacteria (Staphylococcus epidermis, Vibrio parahaemolyticus, Bacillus subtilis, Escherichia coli, ...