Organic Letters 2004-10-28

One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from in situ generated azides.

Alina K Feldman, Benoît Colasson, Valery V Fokin

Index: Org. Lett. 6(22) , 3897-9, (2004)

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Abstract

[reaction: see text] 1,4-Disubstituted 1,2,3-triazoles are obtained in excellent yields by a convenient one-pot procedure from a variety of readily available aromatic and aliphatic halides without isolation of potentially unstable organic azide intermediates.