An Iron Catalyst for Oxidation of Alkyl C H Bonds Showing Enhanced Selectivity for Methylenic Sites

I Prat, L Gómez, M Canta, X Ribas…

Index: Prat, Irene; Gomez, Laura; Canta, Merce; Ribas, Xavi; Costas, Miquel Chemistry - A European Journal, 2013 , vol. 19, # 6 p. 1908 - 1913

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Citation Number: 47

Abstract

The selective functionalization of aliphatic CÀH bonds remains one of the biggest challenges for modern synthetic chemistry.[1] Despite being traditionally considered as inert, alkyl CÀH bonds have been shown to exhibit distinct relative reactivity responding to innate electronic and steric factors.[2] Reagents and catalysts that engage in selective alkyl CÀH bond oxidation reactions, without the aid of covalent interactions, and that do not require ...