A one-pot synthesis of 1, 4-naphthoquinone-2, 3-bis-sulfides catalysed by a commercial laccase

…, R Bokako, N Raseroka, P Steenkamp

Index: Wellington, Kevin W.; Bokako, Refiloe; Raseroka, Nelly; Steenkamp, Paul Green Chemistry, 2012 , vol. 14, # 9 p. 2567 - 2576

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Citation Number: 20

Abstract

Oxidative C–S bond formation with aryl and alkyl thiols was catalysed under mild conditions in a reaction vessel open to air at pH 4.5 and 7.15 in the presence of a commercial laccase (Novozym 51003) and a co-solvent (DMF) to afford 1, 4-naphthoquinone-2, 3-bis-sulfides. The synthesis of 1, 4-naphthoquinone-2, 3-bis-sulfides from two different 1, 4- naphthohydroquinone substrates was investigated with regard to pH and number of ...