A NOVEL METHOD OF ARYLATION OF

M Durandetti, S Sibille, JY Nédélec…

Index: Durandetti; Sibille; Nedelec; Perichon Synthetic Communications, 1994 , vol. 24, # 2 p. 145 - 151

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Abstract

Abstract: Ot—Arylated ketones were obtained in moderate to good yields by onestep electroreductive coupling of Ct—chloroketones and arylhalides in DMF and in the presence of a Al-or Zn-sacrificial anode and a catalytic amount of a nickel complex. l-Aryl—Z— propanones are versatile intermediates for the synthesis of pharmaceuticals, agrochemicals, and fragrances. Two general approaches have been used to arylate ketones at the a- ...