Synthetic communications

Soluble polymer-supported synthesis of α-amino acid derivatives

C Hu, Z Chen, G Yang

Index: Hu, Chunling; Chen, Zuxing; Yang, Guichun Synthetic Communications, 2004 , vol. 34, # 2 p. 219 - 224

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Citation Number: 6

Abstract

View all references Molecules are synthesized on an insoluble solid support where reactions are driven to completion by using excess of reagents, which can be removed by washing with various solvents. However, inherent problems on solid supports are reactive site accessibility, site–site interaction, and monitoring of the reaction. ... View all references The PEG support solubilizes the reacting center in the reaction solvent. After completion of the ...