Biochemistry (New York) 2010-04-01

Structural analysis of lipopolysaccharides from Gram-negative bacteria.

D S Kabanov, I R Prokhorenko

Index: Biochemistry. (Mosc.) 75 , 383-404, (2010)

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Abstract

This review covers data on composition and structure of lipid A, core, and O-polysaccharide of the known lipopolysaccharides from Gram-negative bacteria. The relationship between the structure and biological activity of lipid A is discussed. The data on roles of core and O-polysaccharide in biological activities of lipopolysaccharides are presented. The structural homology of some oligosaccharide sequences of lipopolysaccharides to gangliosides of human cell membranes is considered.