Synthetic Communications®

One-Pot System for Reduction of Epoxides Using NaBH4, PdCl2 Catalyst, and Moist Alumina

S Yakabe

Index: Yakabe, Shigetaka Synthetic Communications, 2010 , vol. 40, # 9 p. 1339 - 1344

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Citation Number: 2

Abstract

Reduction of epoxides with sodium borohydride, a catalytic amount of palladium (II) chloride, and chromatographic neutral alumina preloaded with a small amount of water (moist alumina) in hexane gave alcohols in good to excellent yields and good selectivity of the