Journal of Medicinal Chemistry 1989-01-01

1',2'-seco-dideoxynucleosides as potential anti-HIV agents.

E Abushanab, M S Sarma

Index: J. Med. Chem. 32 , 76, (1989)

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Abstract

1',2'-seco-2',3'-Dideoxycytidine (12), -guanosine (14), -adenosine (16), and -inosine (18) were prepared from (R)-benzylglycidol as potential anti-HIV agents. When compared to ddAdo in protecting ATH8 cells, they were found to be inactive.

Structure	Name/CAS No.	Molecular Formula	Articles
	(R)-(-)-Benzyl glycidyl ether CAS:14618-80-5	C₁₀H₁₂O₂

[Synthesis , 539, (1989)]

[J. Org. Chem. 53 , 4495, (1988)]

[J. Chem. Soc. Chem. Commun. , 291, (1993)]

1',2'-seco-dideoxynucleosides as potential anti-HIV agents.

Abstract

Related Compounds