Australian Journal of Chemistry

Synthesis of 5-Aminopyrazole-4-carbonitriles

MJ Dooley, RJ Quinn, PJ Scammells

Index: Dooley, Michael J.; Quinn, Ronald J.; Scammells, Peter J. Australian Journal of Chemistry, 1989 , vol. 42, # 5 p. 747 - 750

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Citation Number: 11

Abstract

Abstract A one-pot reaction between substituted hydrazines, malononitrile and triethyl orthoformate leads directly to the formation of 1-substituted 5-aminopyrazole-4-carbonitriles. The scope and limitations of this synthetic procedure are discussed in relation to the well