New types of very efficient photolabile protecting groups based upon the [2??(2??nitrophenyl) propoxy] carbonyl (NPPOC) moiety

S Bühler, I Lagoja, H Giegrich, KP Stengele…

Index: Buehler, Sigrid; Lagoja, Irene; Giegrich, Heiner; Stengele, Klaus-Peter; Pfleiderer, Wolfgang Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 620 - 659

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Citation Number: 79

Abstract

Abstract Based upon the photolabile [2-(2-nitrophenyl) propoxy] carbonyl group (NPPOC), a large number of modified 2-(2-nitrophenyl) propanol derivatives substituted at the phenyl ring (see 23–34 and 57–76) as well as at the side-chain (see 85–92 and 95–98) were synthesized to improve the photoreactivity of this new type of photolabile entity. The phenyl moiety was also exchanged by the naphthalenyl group (see 102, 103, 105, 108, 110, 113, ...