Hederasaponin B

Modify Date: 2025-08-25 12:41:46

Hederasaponin B Structure
Hederasaponin B structure
 Common Name Hederasaponin B
CAS Number 36284-77-2 Molecular Weight 1205.379
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C59H96O25 Melting Point 223-226 °C
MSDS N/A Flash Point N/A

 Use of Hederasaponin B


Hederasaponin B, isolated from Hedera helix, has broad-spectrum antiviral activity against various subgenotypes of Enterovirus 71 (EV71).

 Names

Name 3-β-[(O-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranosyl)oxy]olean-12-en-28-oic acid O-α-L-rhamnopyranosyl-(1->4)-β-D-glucopyranosyl-(1-->6)-β-D-glucopyranosyl ester
Synonym More Synonyms

 Hederasaponin B Biological Activity

Description Hederasaponin B, isolated from Hedera helix, has broad-spectrum antiviral activity against various subgenotypes of Enterovirus 71 (EV71).
Related Catalog
References

[1]. Song J, et al. Antiviral Activity of Hederasaponin B from Hedera helix against Enterovirus 71 Subgenotypes C3 and C4a. Biomol Ther (Seoul). 2014 Jan;22(1):41-6.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Melting Point 223-226 °C
Molecular Formula C59H96O25
Molecular Weight 1205.379
Exact Mass 1204.624023
PSA 392.59000
LogP 6.11
Index of Refraction 1.630
InChIKey NVSLBOBPSCMMSO-BVLVEXITSA-N
SMILES CC1OC(OC2C(CO)OC(OCC3OC(OC(=O)C45CCC(C)(C)CC4C4=CCC6C7(C)CCC(OC8OCC(O)C(O)C8OC8OC(C)C(O)C(O)C8O)C(C)(C)C7CCC6(C)C4(C)CC5)C(O)C(O)C3O)C(O)C2O)C(O)C(O)C1O

 Precursor & DownStream

Precursor  1

DownStream  0

 Hederasaponin BBioassay

View more

Name: Cytotoxicity against rat PC12 cells assessed as decrease in cell viability at 50 uM a...
Source: ChEMBL
Target: PC-12
External Id: CHEMBL4136504
Name: Inhibition of COX1 by microplate reader
Source: ChEMBL
Target: Prostaglandin G/H synthase 1
External Id: CHEMBL1177376
Name: Inhibition of COX2 by microplate reader
Source: ChEMBL
Target: Prostaglandin G/H synthase 2
External Id: CHEMBL1177375
Name: Inhibition of pancreatic lipase assessed as umoles of oleic acic released per millimi...
Source: ChEMBL
Target: Pancreatic triacylglycerol lipase
External Id: CHEMBL972809
Name: Cytoprotection against H2O2-induced cell injury in rat PC12 cells assessed as increas...
Source: ChEMBL
Target: PC-12
External Id: CHEMBL4136503
Name: Cytoprotection against amyloid beta (1 to 42)-induced cell injury in rat PC12 cells a...
Source: ChEMBL
Target: PC-12
External Id: CHEMBL4136510
Name: Inhibition of amyloid beta (25 to 35)-induced neuronal degeneration in ddY mouse embr...
Source: ChEMBL
Target: Cortical neurone
External Id: CHEMBL3862786
Name: Cytoprotection against amyloid beta (1 to 42)-induced cell injury in rat PC12 cells a...
Source: ChEMBL
Target: PC-12
External Id: CHEMBL4136508
Name: Cytoprotection against amyloid beta (1 to 42)-induced cell injury in rat PC12 cells a...
Source: ChEMBL
Target: PC-12
External Id: CHEMBL4136509
Name: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL4390549
Total 10, Current Page 1 of 1
1

 Synonyms

Hedera-saponin-B
Hedera saponin B
6-Deoxy-α-L-mannopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-1-O-[(3β)-3-{[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy}-28-oxoolean-12-en-28-yl]-β-D-glucopyranose
hederasaponin B
HederasaponinB
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