CLP257
Published date: 2020-01-06 17:06:19
|
Name | CLP 257 | CAS# | 1181081-71-9 |
|---|---|---|---|---|
| Price | $550.0/100mg $900.0/250mg $1800.0/1g | Purity | 98.0% | |
| Stocking Period |
3 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-DC11507.html | |||
| Detail
Product Information
CLP257 (CLP-257) is a potent, selective K+-Cl- cotransporter KCC2 activator with EC50 of 616 nM; displays selectivity for KCC2 over other KCC family members, NKCC1 and GABAA receptors, and a panel of 55 other receptors; restores impaired Cl(-) transport in neurons, rescues KCC2 plasma membrane expression; renormalizes stimulus-evoked responses in spinal nociceptive pathways in a rat model of neuropathic pain. |