Dicumarol

Published date: 2020-12-18 22:54:27

Dicumarol Structure
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Name Dicoumarol CAS# 66-76-2
Price $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg Purity 98.0%
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Product Webpage: https://www.dcchemicals.com/product_show-Dicumarol.html
 Detail Product Information
Dicoumarol (INN) or dicumarol (USAN) is a naturally occurring anticoagulant that functions as a functional vitamin K depleter (similar to warfarin, a drug that dicoumarol inspired). It is also used in biochemical experiments as an inhibitor of reductases. Like all 4-hydroxycoumarin drugs it is a competitive inhibitor of vitamin K epoxide reductase, an enzyme that recycles vitamin K, thus causing depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes. These compounds are not antagonists of Vitamin K directly—as they are in pharmaceutical uses—but rather promote depletion of vitamin K in bodily tissues allowing vitamin K's mechanism of action as a potent medication for dicoumarol toxicity. The mechanism of action of Vitamin K along with the toxicity of dicoumarol are measured with the prothrombin time (PT) blood test. (Source: https://en.wikipedia.org/wiki/Dicoumarol).

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Price: $66/10mM*1mLinDMSO
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